GE Analytical Instruments' new Sievers 500 RL On-Line TOC Analyzer delivers the accuracy, automation, and confidence needed to transition from laboratory to on-line TOC for enhanced operating efficiencies and science-based risk management. Using the proven Sievers laboratory TOC measurement technology, the Sievers 500 RL provides continuous quality assurance for on-line pharmaceutical water release, cleaning validation, and Process Analytical Technology (PAT) quality initiatives. The reagentless 500 RL features the revolutionary four-port Super iOS standards introduction device that fully automates system protocols, and transfers critical standards information directly to the Analyzer for secure data management, significantly reducing costs and risks. The 500 RL Analyzer shares many productivity and ease-of-use features of other Sievers TOC Analyzers, including 12-month calibration stability, a color touch-screen display, USB port, and minimal maintenance (a few hours per year). With a wide operating range of 0.03 ppb to 2,500 ppb, the 500 RL also measures USP <645> conductivity.